The body naturally produces growth hormones, also referred to at the somatotropin. This is a hormone that is responsible for growth stimulation, cell regeneration, and production in the human body and other animal species. This is a specific type of motigen that is very vital in the development of human body. The HGH consists of a total of 190 amino acids as well as one chain polypeptide secreted, synthesized and stored through the somatotropic antigens found within the pituitary glad. The growth hormone is responsible for raising the concentration of fatty acids and glucose and is also responsible for the stimulated production of IGF-1.
In Drug Prescriptions
A form of HGH referred to as Somatotropin is used in prescription drugs to treat
both adults and children growth disorders. In most states, however, these kind of drugs are only legally available in pharmacies, or through a doctor’s prescription. In recent years, doctors have started prescribing growth hormones for older patients who suffer from GH deficiency, to increase their vitality.
In Anabolism agents
Effects of this hormone on the body tissues can be said to have building effects. Just like it is in other protein generated hormones, the growth hormone works through the interaction of specific receptors on the cell’s surface. Athletes have commonly used this hormone and body builders since the 1980s, although it’s use is prohibited by the National Collegiate Athletic Association. The traditional urine analysis can not detect the use of the HGH drugs. Therefore the ban was not enforced until late in the year 2000. Today, usage of this hormone as a drug to enhance performance is completely banned by the FDA.
In Industrial Agriculture
There are a number of attempts that have been made to try and get approval from different governments to use the growth hormone dairy production in livestock. These efforts have continually been controversial, with only a few states allowing usage of a cow’s specific type of GH referred to as the Bovine Somatotropin to enhance the production of meat and milk in cows. However, retailers are required to label milk containers as having been produced using Bovine Somatotropin.
Structure of the HGH
The major isoform consisted in GH is a protein form of a total of 190 amino acids with a molecular weight of 22,124 Dalton in total. This structure also consists of 4 helices that have the primary function of integrating interaction between the HG receptors and the amino acids. Despite the structural similarities between HGH from a variety of species, only the human and a few primates growth hormone have a significant effect on the human body receptors.
Genes for HGH
The genes in the GH are mostly localized in q22-24 chromosome regions, a close relation to the Human Chorionic Somatomammotropin as well as the prolactin which belongs to a certain form of the homologous cell which has growth promotion and lactogenic activity stimulation characteristics.
Neurosecretory nuclei regulate the secretion of the GH from the pituitary gland. These cells are responsible for the release of peptides which similarly release the growth hormone. The release of the GH in the pituitary glad relies on the balance in these glands, which are in turn affected by different physical stimulation such as sleep, exercise, and diet.